A Mouse Model for Microbeam Radiation Therapy of the Lung

نویسندگان

چکیده

PurposeRadiation therapy is an important treatment component for patients with lung cancer. However, the survival time gained clinical radiation techniques relatively short. Data from preclinical experiments suggest that synchrotron microbeam could be much better suited to control malignant brain tumors than current concepts of therapy. Even at peak doses several hundred gray, extent functional deficits low.Methods and MaterialsWe have developed first mouse model study effects irradiation in tissue.ResultsUp 400 Gy, no acute adverse were seen.ConclusionThis well explore potential cancer response normal tissue organs risk. Radiation low. We tissue. Up seen. This

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15 صفحه اول

Microbeam radiation therapy.

It is proposed to carry out radiotherapy and radiosurgery for brain lesions by crossfiring an array of parallel, closely spaced microbeams of synchrotron-generated x rays several times through an isocentric target, each microbeam in the array having an approximately 25-microns-wide adjustable-height rectangular cross section. The following inferences from the known tissue sparing of 22-MeV deut...

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ژورنال

عنوان ژورنال: International Journal of Radiation Oncology Biology Physics

سال: 2021

ISSN: ['0360-3016', '1879-355X']

DOI: https://doi.org/10.1016/j.ijrobp.2020.12.030